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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4048a18daeb8f6f1fce33a94c91a3dd7816393ec2c9a612f2d0da4368b6e1fba' 
  AND token = 'YhiTxZsdJOmS68Kc0hCtRPraSKTREgaWW1vCn0PWTQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}