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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d3417df82c4db23f708531ed3379c20db8692bf65f9e75e2c1a237c4305490' 
  AND token = 'So2GjvIPStZxn8bNuQOJrSOU8Qiy5u0DOEMX6kSMjNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}