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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed6a0cc9476db5ba378039a9a0b678c295079e807152d8f66616c59a98429cd5' 
  AND token = 'mGGgG1N8fZQjLhcPRrfPTP/WzL0L9FcdCkvk0OMB48M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}